When medical professionals cannot identify physical causes for chronic pain or illness, patients often face frustration and misdiagnosis. Dr. David Clarke, president of the Association for the Treatment of Neuroplastic Symptoms, addresses this medical mystery through his podcast The Story Behind the Symptoms. The series represents the first public doctor-patient conversations exploring neuroplastic pain and illness processes.
Neuroplastic symptoms develop when the brain and nervous system learn pathways in response to stress, trauma, and adversity, frequently beginning in childhood. These conditions include chronic primary pain throughout the body, migraines, fibromyalgia, irritable bowel syndrome, and post-viral syndromes. Approximately 1.5 billion people worldwide experience neuroplastic pain or illness, affecting four out of every ten patients seen by physicians.
Dr. Clarke's approach focuses on uncovering the psychological and emotional roots of physical symptoms. Through his career working with over 7,000 individuals, he has demonstrated that understanding these patterns can lead to healing without invasive procedures or long-term medical treatment. The Association for the Treatment of Neuroplastic Symptoms promotes Neuroplastic Recovery Therapy, an evidence-based biopsychosocial approach that emphasizes uncovering stress, trauma, and unrecognized emotions.
This methodology represents a significant shift from traditional pain management strategies. Neuroplastic Recovery Therapy is the only treatment backed by gold standard science from randomized trials published in top medical journals like the American Medical Association Psychiatry journal, according to Dr. Clarke. The therapy enables patients to gain control over their symptoms without relying on pharmaceuticals, surgery, or expensive treatments, offering a safer and more affordable alternative.
The association recently commissioned the first national survey on neuroplastic pain and illness, with full results scheduled for presentation at their 2025 National Conference in Boulder, Colorado. This research initiative underscores the growing recognition of neuroplastic conditions within the medical community and their impact on global health systems.


